Publications

Our publications on Google Scholar and PubMed.

2024

Chu FY*, Clavijo AS*, Lee S, Zidovska A, Transcription-dependent mobility of single genes and genome-wide motions in live human cells, Accepted, Nature Commun. (2024) *These authors contributed equally
Rautu SA, Zidovska A, Shelley MJ, Spatio-Temporal Dynamics of Nucleo-Cytoplasmic Transport, Accepted, Phys. Rev. Research (2024)
Arsenadze G, Caragine CM, Coakley T, Eshghi I, Yang Y, Wofford A, Zidovska A, Anomalous Coarsening of Coalescing Nucleoli in Human Cells, Biophys. J., 123, 11 (2024) (Selected for Special Issue on Liquid Condensates)
Weady S, Stein DB, Zidovska A, Shelley MJ, Conformations, correlations, and instabilities of a flexible fiber in an active fluid, Phys. Rev. Fluids 9, 013102 (2024) (Editor's Suggestion)

2023

Eshghi I, Zidovska A, Grosberg AY, Model chromatin flows: numerical analysis of linear and nonlinear hydrodynamics inside a sphere, Eur. Phys. J. E., 46, 69 (2023)
Eshghi I, Zidovska A, Grosberg AY, Activity-driven phase transition causes coherent flows of chromatin, Phys. Rev. Lett., 131, 048401 (2023)

2022

Mahajan A, Yen W, Zidovska A*, Saintillan D*, Shelley MJ*, Euchromatin Activity Enhances Segregation and Compaction of Heterochromatin in the Cell Nucleus, PRX, 12, 041033 (2022)
* These authors contributed equally.

In the news:

Phys.org: Stresses and hydrodynamics: Scientists uncover new organzing principles of the genome

VerveTimes: Discovery offers insights into the genome's functionality

Medical News: New insights into biophysical origins of the genome's organization inside the cell nucleus

Featured in Phys.org, December 19, 2022

Eshghi I, Zidovska A, Grosberg AY, Symmetry-Based Classification of Forces Driving Chromatin Dynamics, Soft Matter, 18, 8134 - 8146 (2022)
Weady S, Tong J, Zidovska A, Ristroph L, Anomalous Convective Flows Carve Pinnacles and Scallops in Melting Ice, Phys. Rev. Lett., 128, 044502 (2022)

In the news:

Phys.org: Scientists Uncover How the Shape of Melting Ice Depends on Water Temperature

APS Physics-Focus: Shape of Melting Ice Depends on Temperature

Research Highlight in Nature Reviews Physics: Shapes of Ice and Rock

Cover of January 28, 2022 Issue

Caragine CM, Kanellakopoulos N, Zidovska A, Mechanical Stress Affects Dynamics and Rheology of the Human Genome, Soft Matter, 18, 107-116 (2022)

2021

Wang M, Zinga K, Zidovska A, Grosberg A, Tethered Tracer in a Mixture of Hot and Cold Brownian Particles: Can Activity Pacify Fluctuations?, Soft Matter, 17, 9528-9539 (2021)
Eshghi I, Eaton J, Zidovska A, Interphase Chromatin Undergoes a Local Sol-Gel Transition upon Cell Differentiation, Phys. Rev. Lett., 126, 228101 (2021)

In the news:

EurekAlert: How is the genome like an open book? New research shows cells' 'library system'

Phys.org: How is the genome like an open book? New research shows cells' 'library system'

Featured in Phys.org, June 2, 2021

Zidovska A, Membrane Shape Evolution In Vitro, in: Handbook of Lipid Membranes: Molecular, Functional and Materials Aspects, CRC Press Taylor & Francis, (2021) (Invited Book Chapter)
Zidovska A, Nuclear Espionage, Nature Physics 17 (4), 436-437, (2021)

2020

Zidovska A, Chromatin: Liquid or Solid?, Cell, 183: 1737-1739 (2020)
Zidovska A, The Rich Inner Life of the Cell Nucleus: Dynamical Organization, Active Flows and Emergent Rheology, Biophys. Rev., 12: 1093-1106 (2020)
Eaton J, Zidovska A, Structural and Dynamical Signatures of Local DNA Damage in Live Cells, Biophys. J., 118: 2168-2180 (2020)(Epub Nov 2019)
Zidovska A, The Self-Stirred Genome: Large-Scale Chromatin Dynamics, its Biophysical Origins and Implications, Curr. Opin. Genet. Dev., 61: 83-90 (2020)

Cover of Issue 61, April 2020

2019

Eaton J, Zidovska A, Structural and Dynamical Signatures of Local DNA Damage in Live Cells, Biophys. J. 116, DOI: 10.1016/j.bpj.2019.10.042 (Epub Nov 2019)

In the news:

AAAS: What does DNA's repair shop look like? New research identifies the tools

Futurity: Team pinpoints how the body repairs the damage to DNA

Phys.org: What does DNA's repair shop look like? New research identifies the tools

Featured in Phys.org, Dec. 5, 2019

Caragine CM, Haley SC, Zidovska A, Nucleolar Dynamics and Interactions with Nucleoplasm in Living Cells , eLife, 8: e47533 (2019)

In the news:

eLife Digest: Like oil in water

Phys.org: What keeps cells in shape? New research points to two types of motion

UPI: Dual motion helps cells keep their shape

Cover of issue 8 of eLife, Nov. 2019

2018

Saintillan D, Shelley MJ, Zidovska A, Extensile Motor Activity Drives Coherent Motions in a Model of Interphase Chromatin, Proc. Natl. Acad. Sci. USA, 115:11442-11447 (2018)

In the news:

ScienceDaily: DNA 'dances' in first explanation of how genetic material flows through a nucleus

Caragine CM, Haley SC, Zidovska A, Surface Fluctuations and Coalescence of Nucleolar Droplets in the Human Cell Nucleus, Phys. Rev. Lett., 121, 148101 (2018) (Editor's Suggestion, Featured in Physics)

In the news:

APS Physics-Focus: How to measure viscosity inside cells

AAAS: Scientists get the drop on the cell's nucleus

Featured in Physics 11, 101, Oct. 5, 2018

2017

Zidovska A, Repacking Chromatin for Therapy, Nature Biomed. Eng., 1: 858-859 (2017)
Chu FY, Haley SC, Zidovska A, On the Origin of Shape Fluctuations of the Cell Nucleus, Proc. Natl. Acad. Sci. USA, 114: 10338-10343 (2017)

In the news:

Researchers find 'internal clock' within live human cells

Featured in Phys.org, Sept. 11, 2017

2014

Bruinsma R, Grosberg AY, Rabin Y, Zidovska A, Chromatin Hydrodynamics, Biophys. J., 106: 1871-1881 (2014)

Pre-2014

Zidovska A, Weitz DA, Mitchison TJ, Micron-Scale Coherence in Interphase Chromatin Dynamics, Proc. Natl. Acad. Sci. USA, 110: 15555-15560 (2013) (Selected among “The Best Scientific Visualizations of 2013” by Wired Magazine, Dec 25, 2013)
Oh D, Zidovska A, Xu Y, Needleman DJ, Multi-Point, High-Speed Fluorescence Fluctuation Spectroscopy by Time-Integrated Moment Analysis, Biophys. J., 101: 1546-1554 (2011)
Zidovska A, Ewert KK, Quispe J, Carragher B, Potter CS, Safinya CR, Block Liposome and Nanotube Formation is a General Phenomenon of Membranes Containing Multivalent Lipids, Soft Matter, 7: 8363 (2011)

Cover of issue 18 of Soft Matter, September 2011, Rated “hot article” for Soft Matter

Safinya CR, Raviv U, Needleman DJ, Zidovska A, Choi MC, Ojeda-Lopez MA, Ewert KK, Li Y, Miller HP, Quispe J, arragher B, Potter CS, Kim MW, Feinstein SC, Wilson L, Nanoscale Assembly in Biological Systems: From Neuronal Cytoskeletal Proteins to Curvature Stabilizing Lipids, Adv. Mater., 23: 2260-2270 (2011) (Invited Review Article)
Zidovska A, Sackmann E, On the Mechanical Stabilization of Filopodia, Biophys. J., 100: 1428-1437 (2011)(Rated „Must Read“ on F1000)
Ewert KK, Zidovska A, Ahmad A, Bouxsein NF, Evans HM, McAllister CS, Samuel CE, Safinya CR, Cationic Lipid–Nucleic Acid Complexes for Gene Delivery and Silencing: Pathways and Mechanisms for Plasmid DNA and siRNA, in Topics in Current Chemistry – Nucleic Acid Transfection, 296: 191-226; Eds.: Bielke W, Erbacher C, Springer, Heidelberg & New York (2010) (Invited Book Chapter)
Zidovska A, Ewert KK, Quispe J, Carragher B, Potter CS, Safinya CR, Block Liposomes: Vesicles by Charged Lipids with Distinctly Shaped Nanoscale Sphere-, Pear-, Tube-, or Rod-Segments, in: Liposomes, Methods in Enzymology, edited by N. Duzgunes, Elsevier, 465: 111-128 (2009) (Invited Book Chapter)
Zidovska A, Ewert KK, Quispe J, Carragher B, Potter CS, Safinya CR, The Effect of Salt and pH on Block Liposomes studied by Cryogenic Transmission Electron Microscopy, Biochim. Biophys. Acta, Biomembr., 1788: 1869-1876 (2009)
Zidovska A, Evans HM, Ewert KK, Quispe J, Carragher B, Potter CS, Safinya CR, Liquid Crystalline Phases of Dendritic Lipid–DNA Self-Assemblies: Lamellar, Hexagonal and DNA Bundles, J. Phys. Chem. B, 113: 3694-3703 (2009)
Zidovska A, Evans HM, Ahmad A, Ewert KK, Safinya CR, The Role of Cholesterol and Structurally Related Molecules in Enhancing Transfection by Cationic Liposome–DNA Complexes, J. Phys. Chem. B, 113: 5208-5216 (2009)

Cover of Apr 16, 2009 issue of J. Phys. Chem. B

Zidovska A, Ewert KK, Quispe J, Carragher B, Potter CS, Safinya CR, Block Liposomes from Curvature-Stabilizing Lipids: Connected Nanotubes, -rods, or –spheres, Langmuir, 25: 2979-2985 (2009)

Cover of Mar 3, 2009 issue

Zidovska A, Physicists discover a New Structure of Cationic Lipid-DNA Complexes for Gene Therapy, SLAC Today (Science Today); 19th October (2006)
Ewert KK, Evans HM, Zidovska A, Bouxsein N, Ahmad A, Safinya CR, A Columnar Phase of Dendritic Lipid-Based Cationic Liposome-DNA Complexes for Gene Delivery: Hexagonally Ordered Cylindrical Micelles Embedded in a DNA Honeycomb Lattice, J. Am. Chem. Soc., 128: 3998-4006 (2006)
Zidovska A, Sackmann E, Brownian Motion of Nucleated Cell Envelopes Impedes Adhesion, Phys. Rev. Lett., 96: 04813 (2006)
Sackmann E, Zidovska A, Brownian Motion of Cell Envelopes Controls Adhesion. Abstract of Papers of the American Chemical Society, 230: 1197-1198 (2005)